This classic Florida barrier island is accessible only by boat, but it is worth the ride. A boardwalk takes visitors across mangrove forests and hammocks of live oaks, cabbage palms, paradise trees, and wild limes to a neatly preserved Atlantic beach. During the summer months, the island is an important nesting area for loggerhead, leatherback, and green turtles. They come ashore at night to dig holes in the beach sand where they lay their eggs. The preserve is a favorite for nature students interested in learning about the native flora and fauna of Florida barrier islands. Visitors come to swim, sunbathe, or picnic at the pavilion on the quiet beach. Others make the trip for the great surf fishing. Snorkeling and scuba diving are also popular activities. Located at Port Salerno, on the Intracoastal Waterway, 2/3 of a mile south of the inlet.

Many species of wildlife may be observed at St. Lucie Inlet Preserve State Park, including bobcats, otters, raccoons and more. Morning and late afternoon are the best times to see most wildlife, since it is when they are feeding and most active. The park's varied habitats provide excellent opportunities for birding enthusiasts to view many different species of birdlife. The park is part of the Great Florida Birding Trail. St. Lucie is also a very good place to see wading birds and shorebirds including Great Blue Herons, Brown Pelicans, White Ibis and the Purple Plover.

Annual Entrance Passes can be purchased at all park ranger stations and museums. If you require immediate use of your pass, this is the best option. Passes can be purchased during regular business hours 365 days a year. Please call the park in advance to ensure availability. Those who are eligible for discounted or free passes may use this method to receive their pass. Annual Entrance Passes may be purchased online by visiting the FLORIDA STATE PARKS ANNUALENTRANCE PASSES web page.